December 7, 2013

In that letter you got telling you you were trans before you realized it, the author mentioned the possibility of taking only spiro. Is that actually a thing? I’m sorta in the middle of this whole gender thing at the moment (amab) and that sounds like an appealing option but if my understanding is correct that would leave me without either sex hormone which might have negative effects on my general health?


I’ve heard of some doctors starting their patients on only spiro (or other antiandrogens) for a period of a few months, before adding estrogen. I happened to start on both at once. Everything I’ve heard suggests that spiro-only would be a bad thing on a permanent basis, as sex hormones (either estrogen or testosterone) are supposedly needed for bone health, and taking only spiro would leave you without either.

This is not entirely accurate. The male body has naturally occurring estrogen in it, and spiro doesn’t affect that. Spiro also doesn’t halt T production and absorption entirely; instead, it’s used to bring T down to female levels. Essentially, high dose spiro alone would lead to Male level estrogen and Female level T. Not exactly a medically positive situation, but not life threatening. You’d basically have the hormone levels of a eunuch.

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